MOLECULAR MECHANISM OF THE CELL DEATH INDUCED BY THE HISTONE DEACETYLASE PAN INHIBITOR LBH589 (PANOBINOSTAT) IN WILMS TUMOR CELLS.

Molecular Mechanism of the Cell Death Induced by the Histone Deacetylase Pan Inhibitor LBH589 (Panobinostat) in Wilms Tumor Cells.

Wilms tumor (WT) is an embryonic kidney cancer, for which histone acetylation might be a therapeutic target.LBH589, a novel targeted agent, suppresses histone deacetylases in many tumors.This study investigated the antitumor activity of LBH589 in SK-NEP-1 and G401 cells.SK-NEP-1 and G401 cell growth was assessed by CCK-8 and in nude mice experiment

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Dietary diversity and associated factors among pregnant women attending antenatal care at public health facilities in Bale Zone, Southeast Ethiopia

Sintayehu Hailu,1 Bedasa Woldemichael21Department of Public Health, School of Health Sciences, Goba Referral Hospital, Madda Walabu University, Bale-Goba, Ethiopia; 2Department of Nursing, School of Health Sciences, Goba Referral Hospital, Madda Walabu University, Bale-Goba, EthiopiaBackground: Dietary diversity is a proxy indicator of nutrient ade

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